For the treatment of adults with moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy
For the treatment of adults with moderate to severe PLAQUE psoriasis
who are candidates for systemic therapy or phototherapy
SKIN CLEARANCE SHOULD
STAND THE TEST OF TIME†
*IL=interleukin.
†Test of time refers to 48 weeks.
In VOYAGE 1, 837 patients were randomized to placebo (n=174), TREMFYA® 100 mg every 8 weeks (q8w) after Weeks 0 and 4 (n=329), or Humira® (adalimumab) 80 mg at Week 0, 40 mg at Week 1, and 40 mg every 2 weeks thereafter (n=334). Eligible patients (≥18 years of age) had moderate to severe plaque psoriasis (ie, Investigator's Global Assessment [IGA] score ≥3, Psoriasis Area and Severity Index [PASI] score ≥12, body surface area [BSA] involvement ≥10%) for at least 6 months and were candidates for systemic therapy or phototherapy. The study comprised a placebo-controlled period (Weeks 0 to 16) after which patients taking placebo crossed over to receive TREMFYA® at Weeks 16 and 20 and q8w thereafter through Week 48 and an active-comparator–controlled period when TREMFYA® was compared with Humira® from Week 0 through Week 48.1
Please see complete Study Design.TREMFYA® (guselkumab) is a registered trademark of Janssen Biotech, Inc. Humira® (adalimumab) is a registered trademark of AbbVie Inc.
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