~90% patient retention through 2 years with TREMFYA®1*

Patients continued therapy through Week 100 in DISCOVER 2

Patient Retention Data in DISCOVER 2 (Week 24 and through Week 100)

Patient retention data in DISCOVER 2 Week 24 and through Week 100
Zoom out
Zoom in
Patient retention data in DISCOVER 2 Week 24 and through Week 100

Reasons for discontinuation included: adverse event, lack of efficacy, withdrawn consent, lost to follow-up, death, and other.

No conclusions regarding clinical efficacy or safety can be drawn.

q8w=every 8 weeks.

*Year 2 represents Week 100.

Patient retention data in DISCOVER 2 (Week 24 and through Week 100) and in DISCOVER 1 (Week 24 and prior to Week 48)1

Patient retention data in DISCOVER 2 Week 24 and through Week 100 and in DISCOVER 1 Week 24 and prior to Week 48
Zoom out
Zoom in
Patient retention data in DISCOVER 2 Week 24 and through Week 100 and in DISCOVER 1 Week 24 and prior to Week 48

No conclusions regarding clinical efficacy or safety can be drawn.

FDA=U.S. Food and Drug Administration; q4w=every 4 weeks.

*Discontinuations shown for patients who were randomized and received at least 1 study drug administration.

248 patients in DISCOVER 2 were randomized to TREMFYA® 100 mg q8w dosing regimen through Week 112; TREMFYA® q4w was not an FDA-approved dosing regimen.

1 patient-initiated, protocol-prohibited medication in the placebo group through Week 24.

Reference: 1. Data on file. Janssen Biotech, Inc.