TREMFYA^® offers one single subcutaneous (SC) pen injection for each maintenance dose¹

DOSING OPTIONS

TREMFYA^® dosing for UC

Not actual size.

Induction Dosing¹

3 IV Infusions (200 mg)*

200-mg IV infusion administered over at least 1 hour

*200 mg/20 mL (10 mg/mL) solution in a single-dose vial.¹

Not actual
size.

Maintenance Dosing¹

TREMFYA^® PEN (200 mg)^†

200 mg administered by SC injection at Week 12, and every 4 weeks thereafter

Also available in prefilled syringe (200 mg/2 mL)

Also available in prefilled syringe (200 mg/2 mL)

OR

Not actual
size.

OR

TREMFYA^® PEN (100 mg)^‡

100 mg administered by SC injection at Week 16, and every 8 weeks thereafter

Also available in One-Press patient-controlled injector or prefilled syringe (100 mg/mL)

Also available in One-Press patient-controlled injector or prefilled syringe (100 mg/mL)

Use the lowest effective recommended dosage to maintain therapeutic response.

^†200 mg/2 mL in a single-dose prefilled pen.¹

^‡100 mg/mL in a single-dose prefilled pen.¹

Pretreatment Evaluations: Evaluate for tuberculosis (TB) infection, obtain liver enzymes and bilirubin levels, and complete all age-appropriate vaccinations according to current immunization guidelines.¹

Monitor: For signs and symptoms of active TB during and after treatment with TREMFYA^®; liver enzymes and bilirubin levels for at least 16 weeks of treatment, and periodically thereafter according to routine patient management.¹

TREMFYA^® is intended for use under the guidance and supervision of a healthcare professional. TREMFYA^® may be administered by a healthcare professional, or a patient/caregiver after proper training on correct subcutaneous injection technique.¹

IV=intravenous; SC=subcutaneous.

DEVICES

For your patients’ maintenance doses, TREMFYA^® is available as 3 different devices¹

200 mg/2 mL

TREMFYA^® PEN

Not actual size.

TREMFYA^® PEN

TREMFYA^® comes in a single-dose prefilled pen containing one 200-mg dose. Each TREMFYA^® PEN can be used only one time.

Prefilled syringe

Not actual size.

Prefilled syringe

TREMFYA^® comes as a single-dose prefilled syringe containing one 200-mg dose. Each TREMFYA^® prefilled syringe can be used only one time.

Also in

100 mg/mL¹

TREMFYA^® PEN

Not actual size.

TREMFYA^® PEN

TREMFYA^® comes in a single-dose prefilled pen containing one 100-mg dose. Each TREMFYA^® PEN can be used only one time.

One-Press

Not actual size.

One-Press

TREMFYA^® comes in a single-dose One-Press patient-controlled injector containing one 100-mg dose. Each One-Press injector can be used only one time.

Prefilled syringe

Not actual size.

Prefilled syringe

TREMFYA^® comes as a single-dose prefilled syringe containing one 100-mg dose. Each TREMFYA^® prefilled syringe can be used only one time.

At induction, there is a 200-mg IV infusion administered over at least 1 hour at Week 0, Week 4, and Week 8.¹

In maintenance, once you have determined the appropriate dose for your patient, you and your patient can choose which device may be best suited for them.

Use the lowest effective recommended dosage to maintain therapeutic response.

Please see the full Instructions for Use for the TREMFYA^® PEN, One-Press patient-controlled injector, and prefilled syringe.

PRESCRIBING TREMFYA^®

Write 2 prescriptions for TREMFYA^®1

Write 1 prescription for induction dosing and 1 prescription for maintenance dosing

Write one Rx for TREMFYA^® UC IV Induction (200 mg IV q4w).*

The recommended induction dosage of TREMFYA^® is 200 mg administered by intravenous infusion over at least 1 hour at Week 0, Week 4, and Week 8.

Write one Rx for TREMFYA^® UC SC Maintenance (200 mg SC q4w or 100 mg SC q8w).

The recommended maintenance dosage of TREMFYA^® is:

200 mg administered by subcutaneous injection at Week 12, and every 4 weeks thereafter^†‡

100 mg administered by subcutaneous injection at Week 16, and every 8 weeks thereafter^†‡§

Use the lowest effective recommended dosage to maintain therapeutic response.

Please refer to the full Prescribing Information for the complete dosing information.

*200 mg/20 mL (10 mg/mL) solution in a single-dose vial.

^†200 mg/2 mL or 100 mg/mL in a single-dose prefilled pen.

^‡200 mg/2 mL or 100 mg/mL in a single-dose prefilled syringe.

^§100 mg/mL in a single-dose One-Press patient-controlled injector.

IV=intravenous; q4w=every 4 weeks; q8w=every 8 weeks; SC=subcutaneous; SUBQ=subcutaneous.

*200 mg/20 mL (10 mg/mL) solution in a single-dose vial.

^†200 mg/2 mL or 100 mg/mL in a single-dose prefilled pen.

^‡200 mg/2 mL or 100 mg/mL in a single-dose prefilled syringe.

^§100 mg/mL in a single-dose One-Press patient-controlled injector.

IV=intravenous; q4w=every 4 weeks; q8w=every 8 weeks; SC=subcutaneous; SUBQ=subcutaneous.

These videos are not meant to replace the Instructions for Use (IFU) that are supplied with TREMFYA^®. Instruct patients to read the IFU before using their TREMFYA^® PEN, TREMFYA^® prefilled syringe, or One-Press patient-controlled injector and each time they get a refill. Please see the full IFU for TREMFYA^®.