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TREMFYA® SC PEN

Not actual size.

When patients were asked to select which device they prefer:

~9out of10

preferred an SC pen

over an on-body injector (OBI) for treatment management4*†

*In a third-party 2025 unbranded market research survey, 506 patients with Crohn’s disease or ulcerative colitis were asked to choose which administration method they would prefer for the treatment of disease between an SC injection pen and an SC OBI device. It did not evaluate efficacy or safety. While these factors are important, there are additional considerations for selecting treatment.4

†TREMFYA does not offer an SC OBI device.

Options for Administration

INDUCTION DOSING1

TREMFYA® PEN SC Induction Packs
Not actual size.

INDUCTION—SC

3 SC TREMFYA PEN
Induction Packs*

400 mg SC injection (given as two consecutive injections of 200 mg each) at Weeks 0, 4, and 8

Dosing schedule: Week 0, Week 4, and Week 8

TREMFYA is also available in 200 mg prefilled syringes

OR

Dosing schedule: Week 0, Week 4, and Week 8

TREMFYA is also available in 200 mg prefilled syringes

OR

IV infusion
IV infusion
Not actual size.

INDUCTION—IV

IV infusion (200 mg)† -

3 IV induction doses

200 mg IV infusion administered over at
least 1 hour at Weeks 0, 4, and 8

Dosing schedule: Week 0, Week 4, and Week 8
Dosing schedule: Week 0, Week 4, and Week 8

*Induction Pack for Crohn’s disease: Carton containing two 200 mg/2 mL single-dose prefilled pens (400 mg/4 mL total) (TREMFYA PEN).1

†200 mg/20 mL (10 mg/mL) solution in a single-dose vial.1

MAINTENANCE DOSING1

TREMFYA® PEN (200 mg)
Not actual size.

TREMFYA PEN
(200 mg)1‡

200 mg administered by SC injection at
Week 12, and every 4 weeks thereafter

Maintenance dosing for TREMFYA® PEN (200 mg): administered by SC injection at Week 12 and every 4 weeks thereafter

Also available in prefilled syringe (200 mg/2 mL)

Maintenance dosing for TREMFYA® PEN (200 mg): administered by SC injection at Week 12 and every 4 weeks thereafter

Also available in prefilled syringe (200 mg/2 mL)

OR

TREMFYA® PEN (100 mg)
Not actual size.

TREMFYA PEN
(100 mg)1§

100 mg administered by SC injection at Week 16, and every 8 weeks thereafter

Maintenance dosing for TREMFYA® PEN (100 mg): administered by SC injection at Week 16 and every 8 weeks thereafter

Use the lowest effective recommended dosage to maintain therapeutic response.

Also available in One-Press patient-controlled injector
(100 mg/mL) or a prefilled syringe (200 mg/2 mL and 100 mg/mL).

Maintenance dosing for TREMFYA® PEN (100 mg): administered by SC injection at Week 16 and every 8 weeks thereafter

Use the lowest effective recommended dosage to maintain therapeutic response.

Also available in One-Press patient-controlled injector (100 mg/mL) or a prefilled syringe (200 mg/2 mL and 100 mg/mL).

‡200 mg/2 mL in a single-dose prefilled pen.1

§100 mg/mL in a single-dose prefilled pen.1

Pretreatment Evaluations: Evaluate for tuberculosis (TB) infection, evaluate liver enzymes and bilirubin levels, and complete all age-appropriate vaccinations according to current immunization guidelines.1

Monitor: For signs and symptoms of active TB during and after treatment with TREMFYA; liver enzymes and bilirubin levels for at least 16 weeks of treatment, and periodically thereafter according to routine patient management.1

TREMFYA is intended for use under the guidance and supervision of a healthcare professional. After proper training in subcutaneous injection technique, adults may self-inject.1

DDD=Drug Distribution Data; IL-23=interleukin-23; IL-23i=interleukin-23 inhibitor; IV=intravenous; NPA=National Prescription Audit; SC=subcutaneous; UC=ulcerative colitis.

HOW TO PRESCRIBE

Write 2 prescriptions for TREMFYA1

Write 1 prescription for induction dosing and 1 prescription for maintenance dosing 

RX for TREMFYA® PEN Induction Pack or TREMFYA® 200 mg IV
RX for TREMFYA® 200 mg SUBQ or TREMFYA® 100 mg SUBQ
RX for TREMFYA® PEN Induction Pack or TREMFYA® 200 mg IV
RX for TREMFYA® 200 mg SUBQ or TREMFYA® 100 mg SUBQ

Write one Rx for TREMFYA for induction dosing and one Rx for maintenance dosing  

Recommended Dosing for Crohn’s Disease:

  • Induction Dose: 400 mg administered by SC injection (given as two consecutive injections of 200 mg each) at Weeks 0, 4, and 8 or 200 mg administered by intravenous infusion over at least 1 hour at Weeks 0, 4, and 8
  • Maintenance Dose: 100 mg administered by subcutaneous injection at Week 16, and every 8 weeks thereafter, or 200 mg administered by subcutaneous injection at Week 12, and every 4 weeks thereafter. Use the lowest effective recommended dosage to maintain therapeutic response

Please refer to the full Prescribing Information for the complete dosing information.

Pretreatment Evaluations: Evaluate for tuberculosis (TB) infection, evaluate liver enzymes and bilirubin levels, and complete all age-appropriate vaccinations according to current immunization guidelines.1

Monitor: For signs and symptoms of active TB during and after treatment with TREMFYA; liver enzymes and bilirubin levels for at least 16 weeks of treatment, and periodically thereafter according to routine patient management.1

TREMFYA is intended for use under the guidance and supervision of a healthcare professional. After proper training in subcutaneous injection technique, adults may self-inject.1

IV=intravenous; q4w=every 4 weeks; q8w=every 8 weeks; SC=subcutaneous; SUBQ=subcutaneous. 

DEVICES

TREMFYA is available with 3 different devices for your patients1

200 mg/2 mL1

TREMFYA PEN

TREMFYA® PEN 200-mg dose
TREMFYA® PEN 200-mg dose

Not actual size.

TREMFYA PEN

TREMFYA comes in a single-dose prefilled pen containing one 200 mg dose. Each TREMFYA PEN can be used only one time.

OR

Prefilled syringe

TREMFYA® prefilled syringe 200-mg dose

Not actual size.

Prefilled syringe

TREMFYA comes in a single-dose prefilled syringe containing one 200 mg dose. Each TREMFYA prefilled syringe can be used only one time.

Also in

100 mg/mL1

TREMFYA PEN

TREMFYA® PEN 100-mg dose

Not actual size.

TREMFYA PEN

TREMFYA comes in a single-dose prefilled pen containing one 100 mg dose. Each TREMFYA PEN can be used only one time.

OR

Prefilled syringe

TREMFYA® prefilled syringe 100-mg dose
TREMFYA® prefilled syringe 100-mg dose

Not actual size.

Prefilled syringe

TREMFYA comes in a single-dose prefilled syringe containing one 100 mg dose. Each TREMFYA prefilled syringe can be used only one time.

OR

One-Press

TREMFYA® One-Press injector 100-mg dose

Not actual size.

One-Press

TREMFYA comes in a single-dose One-Press patient-controlled injector containing one 100 mg dose. Each One-Press injector can be used only one time.

Once you have determined the appropriate dose for your patient, you and your patient can choose which device may be best suited for them.1

Please see the full Instructions for Use for the TREMFYA PEN, One-Press patient-controlled injector, and prefilled syringe.

DEMONSTRATION VIDEOS

These videos are not to replace the Instructions for Use (IFU) that are supplied with TREMFYA. Instruct patients to read the IFU before using their TREMFYA PEN, TREMFYA prefilled syringe, or One-Press patient-controlled injector and each time they get a refill. Please see the full IFU for TREMFYA.

TREMFYA PEN demonstration

Video Play

TREMFYA prefilled syringe demonstration

Video Play

TREMFYA One-Press demonstration

Video Play

TREMFYA is intended for use under the guidance and supervision of a healthcare professional. After proper training in subcutaneous injection technique, adults may self-inject.1

teal vector
teal vector
teal vector

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APP=advanced practice provider.

References: 1. TREMFYA [Prescribing Information]. Horsham, PA: Janssen Biotech, Inc. 2. Skyrizi® [Prescribing Information]. North Chicago, IL: AbbVie Inc. 2026. 3. Omvoh® [Prescribing Information]. Indianapolis, IN: Eli Lilly and Company. 2025. 4. Data on file. Janssen Biotech, Inc.